About 2 results found for searched term "Osilodrostat (LCI699)" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5233 | Osilodrostat (LCI699) | Mineralocorticoid Receptor |
| Osilodrostat | ||
| Osilodrostat (LCI699) is a potent inhibitor of human 11β -hydroxylase and aldosterone synthase with IC50 values of 2.5 and 0.7nM, respectively. | ||
| M28169 | Osilodrostat phosphate | Mineralocorticoid Receptor |
| LCI699 phosphate | ||
| Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. | ||
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